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People are being asked to stay inside and follow police advice as the emergency services respond to a serious incident in Plymouth.
Local MP Luke Pollard tweeted: "Really worrying news coming out of Keyham."
He said: "Please can everyone stay safe, stay indoors and follow police advice."
The ambulance service said it was called at 18:12 BST and has sent "a significant number of resources" to the scene.
The BBC is not responsible for the content of external sites. View original tweet on TwitterSouth Western Ambulance Service said it was responding with "Hazardous Area Response Teams (HART), multiple ambulances, air ambulances, multiple doctors and senior paramedics".
Mr Pollard added: "I've spoken to some local residents and the police and the situation looks very serious indeed.
"Please avoid speculation and please do not share images of any victims. Please keep our community in your thoughts and prayers."
He later tweeted: "Update: awaiting confirmation of number of victims but this looks like a very grim day for our city and our community.
"Please can I ask that you think of the families and our community and not share any images or videos of any of the victims. #keyham."
A number of police vehicles are on the scene and some roads have been closed.
MP for Plymouth Moor View Johnny Mercer tweeted he was aware of a "serious and tragic incident unfolding in Plymouth" and asked people not to post rumour and speculation on social media.
The BBC is not responsible for the content of external sites. View original tweet on TwitterAt the scene
Scott Bingham, BBC South West
I'm standing on Wolseley Road, one of the main routes through Plymouth and it is currently closed in both directions around Henderson Place with traffic being diverted.
There's a huge police presence here, I've lost count of the number of police vehicles.
Just where I'm standing I can see at least half a dozen.
There are three ambulances and we've just seen four air ambulances actually take off from the scene here, so there's a huge amount going on.
We do not have any confirmed official details from the police yet other than that the incident is ongoing.
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